2021 Mercedes-Benz E-Class reliability

Is it reliable?

Owners have filed 20 complaints with NHTSA about the 2021 Mercedes-Benz E-Class over 6 years — 3 per year. That is the fewest complaints per year among the 13 E-Class years on this site. NHTSA has no recalls on file for this model year.

2012 Mercedes-Benz E-Class
Photo by Navigator84, resized from the original. Wikimedia Commons CC BY-SA 3.0
Complaints

20

Per year

3

Recalls

0

Years on the road

6

What owners report

The complaints owners file most often name Electrical system (7 of 20), then Engine (6) and Back-over prevention (3). Those filings include 1 that reports a fire.

Next to 2020 and 2022

The 2020 E-Class has 20 complaints, 3 per year, and the 2022 has 21 complaints, 6 per year. The 2021 has fewer complaints per year than the 2020. The 2021 has fewer complaints per year than the 2022.

The complaint rate is complaints filed in this year’s first 3 years on the road, divided by however many of those years have passed. Recalls are a separate count. The numbers are for the US-market 2021 Mercedes-Benz E-Class. How we count. Data as of .

Recalls (0)

No recalls on file with NHTSA for this model year.

Complaints by component (20 total)

Electrical system
7
Engine
6
Back-over prevention
3
Powertrain
3
Fuel and propulsion system
2
Fuel system, gasoline
1
Service brakes
1
Wheels
1
Crash-flagged

0

Fire-flagged

1

Injury reports

0

Death reports

0

Complaints filed per year

520212202212023520244202532026
Excerpts from recent NHTSA complaint filings
  • "Engine misfires, lower engine power, and a lit check engine/Malfunction Indicator Lamp. Mercedes-Benz issued an Emission Service Campaign (No. 2021070006, internal code 21P1590208) to replace out-of-spec ignition coils…"
    Powertrain · filed 2026-08-08
  • "Vehicle: 2021 Mercedes-Benz E350 Sedan (W213) VIN: [XXX] While operating the vehicle, the diagnostic system displayed the fault code P240200 related to the Evaporative Emission Control System (EVAP). The warning message…"
    Electrical system, Fuel and propulsion system · filed 2026-05-08
  • "With the car only have about 15,000 miles the transmission has failed . I have seen there have been recalls of other models with similar complaints of transmission failure ."
    Powertrain · filed 2026-01-04
  • "Engine keeps having a misfire that Mercedes put a TSB out for and once the misfire happen I cause the vehicle to go in a limp mode which causes the vehicle to loose power happened to me in the freeway. The car had 54K…"
    Engine · filed 2025-12-27
  • "My 2021 Mercedes-Benz E350 (VIN [XXX] ) developed a serious engine issue involving cylinder misfire and check engine light. The dealer diagnosed it as a leaking exhaust valve on cylinder 4, related to TSB…"
    Engine · filed 2025-07-14

NHTSA crash ratings

Version Overall Front Side Rollover
2021 Mercedes-Benz E-Class 2DR 4WD Not rated Not rated Not rated Not rated
2021 Mercedes-Benz E-Class 2DR RWD Not rated Not rated Not rated Not rated
2021 Mercedes-Benz E-Class 4 DR 4WD 5 stars 5 stars 5 stars 5 stars
2021 Mercedes-Benz E-Class 4 DR RWD 5 stars 5 stars 5 stars 5 stars
2021 Mercedes-Benz E-Class Cabriolet C 4WD Not rated Not rated Not rated Not rated
2021 Mercedes-Benz E-Class Cabriolet C RWD Not rated Not rated Not rated Not rated
2021 Mercedes-Benz E-Class SW 4WD 5 stars 5 stars 5 stars 5 stars
2021 Mercedes-Benz E-Class SW RWD 5 stars 5 stars 5 stars 5 stars

Stars are how this vehicle did in NHTSA crash tests. They are a safety result, separate from the complaint record. Not rated means that test was not run for this version.

Specs and fitment

W213, 2017–2023
Body styles Sedan
Oil 0W-40 full synthetic (MB-approved; common US E300 fill) , 4.5 qt capacity
Tire size 225/55R17 to 245/40R19 (trim-dependent; E300 pages)

Known issues for this generation

For 2017 E300 sedans, NHTSA campaign 17V-076 covers certain 2017 E300, E300 4Matic, and E43 AMG vehicles: the front passenger occupant detection control unit may be incorrectly installed so an adult can be misclassified and the passenger air bag deactivated; dealers inspect the pressure hose and replace the hose and detection mat if needed. Campaign 18V-271 covers certain 2017 E300 and related models where headlight horizontal adjustment screws may lack a required sealing cap (FMVSS noncompliance); dealers retrofit sealing caps. Campaign 20V-449 covers certain 2017-2019 E300 vehicles that previously had the instrument cluster replaced, for seat-belt warning software that may not sound or blink correctly; dealers update cluster software.

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Frequently asked questions

Is the 2021 Mercedes-Benz E-Class reliable?

Owners have filed 20 complaints with NHTSA about the 2021 Mercedes-Benz E-Class over 6 years — 3 per year. That is the fewest complaints per year among the 13 E-Class years on this site. NHTSA has no recalls on file for this model year.

What are common problems with a 2021 Mercedes-Benz E-Class?

The complaints owners file most often name Electrical system (7 of 20), then Engine (6) and Back-over prevention (3). Those filings include 1 that reports a fire.

Is the 2021 Mercedes-Benz E-Class more reliable than the years next to it?

The 2020 E-Class has 20 complaints, 3 per year, and the 2022 has 21 complaints, 6 per year. The 2021 has fewer complaints per year than the 2020. The 2021 has fewer complaints per year than the 2022.

Has the 2021 Mercedes-Benz E-Class been recalled?

NHTSA has no recalls on file for the 2021 Mercedes-Benz E-Class.

How many complaints have owners filed about the 2021 Mercedes-Benz E-Class?

Owners have filed 20 complaints about the 2021 Mercedes-Benz E-Class with NHTSA.

What generation is the 2018 Mercedes-Benz E-Class?

W213 generation (2017-2023).

What oil does a US Mercedes-Benz E-Class typically take?

Generation notes list MB-approved 0W-40 full synthetic for common US E350/E300 fills; confirm the approval sheet in the manual.

What tire sizes does a Mercedes-Benz E-Class use?

Sizes vary widely by chassis and trim; W213 E300 pages span about 225/55R17 to 245/40R19.